Modafinil and Wellbutrin. Which one is better and is it OK to mix them?
At first, let’s compare Modafinil vs Wellbutrin and choose the best drug.
So, Modafinil is a nootropic, which means it’s very good for improving the cognitive functions of a patient. It can improve focus, motivation and concentration, as well as give you energy and improve your memory, but the main Modafinil effect is that it can make you alert and awake. It was initially designed to treat sleeping problems, and it’s very good at it — well, it’s also a perfect smart drug. Why “perfect”? Because it isn’t only good as a cognitive enhancer, it’s also a very safe medication, unlike other nootropics. The side effects are rare and not dangerous, Modafinil is also not addictive and you can safely take it for a long time. That’s why Provigil (brand name of Modafinil, these words are actually synonyms) is one of the best smart drugs in the world and probably the best one.
But, in order to compare Modafinil and Wellbutrin, we should talk about the second medication, too.
So, Wellbutrin is also called Bupropion, and here we see the same situation as with Provigil and Modafinil. Bupropion is the name of the active substance while Wellbutrin is a brand name. This medication can treat depressive disorders. There are some other effects of this drug (like, it can treat seasonal affective disorder), but we can safely say that Wellbutrin is an antidepressant drug. But why should we compare a nootropic and antidepressant, what do they have in common?
Because both Provigil and Wellbutrin are stimulants. Both of these medications can give you energy boosts, and that’s why we’ve decided to compare Provigil vs Wellbutrin.
Modafinil is often used off-label. It’s officially a drug that should be used to treat narcolepsy, but the great majority of patients use it as a stimulant and smart drug. The same can’t be said about Wellbutrin. This drug was approved by the FDA as a treatment of depression, and that’s exactly why people take it. It’s also a good stimulant, and (surprise!) it’s good for those who want to stop smoking. Modafinil isn’t used for this purpose, while Wellbutrin can’t improve your memory, motivation and focus. We’ll compare them as drugs for anxiety and tiredness (but neither Modafinil nor Wellbutrin are approved for treating these conditions).
While Modafinil is one of the most safe stimulants, Bupropion isn’t that good. Patients who take it can have such problems as anxiety, panic, problems with sleeping, depression and even suicidal thoughts. These side effects are also more common than Modafinil ones. Those with heart, liver and kidney diseases should be careful while taking both Modafinil and Bupropion.
Let’s now talk about overdosing and addiction to these medications. According to the clinical researches (and some real-life cases), Modafinil is safe even if a patient overdoses. Thus, 25 daily doses resulted in headache, nausea and arrhythmia, but no serious problems happened. That doesn’t mean you should overdose and exceed your dose, it’s just another evidence that Modafinil is very safe. Again, we can’t say the same about Wellbutrin. Overdosing on this medication can be fatal, so don’t ever take more than needed and if you feel something is going wrong after taking a pill, call the Poison help line immediately.
When comparing Provigil and Wellbutrin, it’s necessary to talk about whether these drugs are addictive or not. We know that Modafinil is not addictive (there were a very few patients with such problems during the last 20 years), but Wellbutrin can be. It’s not considered to be a very addictive drug, of course, but it’s not as safe as Modafinil — sometimes if patients crush pills and inhale them, it can lead to the tolerance and addiction.
But what about the improvement of mental or physical functions?
Here we can say that both of them are very good. Modafinil acts more softly, you don’t feel it like you’re high — with this drug you just become smarter, more concentrated and more focused. Wellbutrin acts a little bit different, but it’s a very good stimulant, too. Moreover, it can help you with your depression, and in this sphere it’s even better than Modafinil. But if you need a smart drug, a perfect and safe nootropic without serious side effects — Modafinil would be the best choice for you. If you want a drug that would help you to quit smoking and to cope with your depression — Wellbutrin would be good in such cases.
Taking them together. Does it make sense?
Well, there were no clinical researches and trials, so this part of the text will be based on feedbacks and amateur researches.
In short, you can take them together if you want to. There are no reports on dangerous interactions of these two drugs, moreover they can complement each other. Thus, seizures are one of the most common side effect of Wellbutrin, and Modafinil can reduce the probability of seizures to a minimum. By mixing them, you will get great energy, motivation boost, improved concentration and memory (Modafinil effects) and improved mood as well as you will cope with your tiredness (Wellbutrin effects). Just be careful and tell your doctor if you have any problems, because, as we’ve just said — no clinical trials were held on such a combination.